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45 - PHR - Pharmaceutical Sciences

PHR 114 - Introduction to Pharmacokinetics

Code	Start Date	Duration	Venue
PHR 114	30 December 2024	5 Days	Istanbul	Registration Form Link
PHR 114	27 January 2025	5 Days	Istanbul	Registration Form Link
PHR 114	24 March 2025	5 Days	Istanbul	Registration Form Link
PHR 114	19 May 2025	5 Days	Istanbul	Registration Form Link
PHR 114	14 July 2025	5 Days	Istanbul	Registration Form Link
PHR 114	08 September 2025	5 Days	Istanbul	Registration Form Link
PHR 114	03 November 2025	5 Days	Istanbul	Registration Form Link
PHR 114	29 December 2025	5 Days	Istanbul	Registration Form Link

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Course Description

The course presents fundamental pharmacokinetic concepts in a manner that will allow participants without a specific pharmacokinetic background to apply these principles to their work. The emphasis will be on conceptual understanding with supporting methods to encourage active learning and long-term retention. Basic concepts of clearance, volume of distribution, and bioavailability will be presented and applied to absorption, distribution, metabolism, and excretion of drugs.

This course gives a basic understanding of pharmacokinetics and pharmacodynamics to either further their own work or to more effectively interact with scientists involved in pharmacokinetic and drug delivery research. Concepts covered in this course are essential in the evaluation of traditional dosage forms and innovative medical delivery systems and devices.

Course Objectives

Understanding the requirements for ADME
Knowing about PK/TK, and DM studies conducted to select the optimal drug discovery lead
Supporting first-in-human clinical trials (preclinical studies)
Comparing metabolism profiles from animal models to humans (nonclinical / clinical evaluations)

Who Should Attend?

Personnel in the pharmaceutical and biotechnology industries
Contract research organizations (CROs) who need to understand the principles and requirements for ADME
Personnel working in drug discovery and the preclinical/nonclinical and clinical development processes
Nonclinical and clinical scientists and managers
Project team leaders at pharmaceutical companies and related industries
Those who seek information to support submissions to regulatory authorities

Course Details/Schedule

Day 1

Pharmacokinetics - definitions and terminology
Physiological aspects of drug absorption, distribution and elimination
Ideal pharmacokinetic parameters of a new drug preparation.
Assessment of pharmacokinetic parameters

Day 2

Assessment of rate and extent of drug absorption; bioavailability
How do we optimize PK for new compounds
Reasons behind why some drug candidates fail
Processes involved in PK

Day 3

Absorption
PK study examples and case studies
Distribution
Whole-body autoradiography example

Day 4

Metabolism
Discussion
Excretion

Day 5

Multiple Dosing
Discussion
Allometric scaling between species

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SAHARA Group Training and Consultancy INC (in Turkish: SAHARA Group Eğitim ve Danışmanlık AŞ)

Tax Office: Beyoğlu (Istanbul/Turkiye,Tax No: 7390525151 (Vergi Dairesi: Beyoğlu (İstanbul), Vergi No: 7390525151)

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45 - PHR - Pharmaceutical Sciences

PHR 114 - Introduction to Pharmacokinetics

Course Description

Course Objectives

Who Should Attend?

Course Details/Schedule

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